{"id":1537,"date":"2023-01-13T16:21:41","date_gmt":"2023-01-13T16:21:41","guid":{"rendered":"http:\/\/mitotag.com\/?page_id=1537"},"modified":"2023-11-06T17:03:39","modified_gmt":"2023-11-06T17:03:39","slug":"elementor-1537","status":"publish","type":"page","link":"https:\/\/mitotag.com\/?page_id=1537","title":{"rendered":"Mitoboost V2.0"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1537\" class=\"elementor elementor-1537\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9bc1c7b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9bc1c7b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-11832ac\" data-id=\"11832ac\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a944dc4 elementor-widget elementor-widget-heading\" data-id=\"a944dc4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">|MitoBOOST v2.0<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5d4439c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5d4439c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6826193\" data-id=\"6826193\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-56807ac elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"56807ac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f2491b9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f2491b9\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-83c4f64\" data-id=\"83c4f64\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-823ea5e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"823ea5e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-b1d7af6\" data-id=\"b1d7af6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4b21741 elementor-widget elementor-widget-image\" data-id=\"4b21741\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"315\" height=\"77\" src=\"https:\/\/mitotag.com\/wp-content\/uploads\/2020\/07\/centro-2020_colored_b-2.png\" class=\"attachment-large size-large wp-image-1271\" alt=\"\" srcset=\"https:\/\/mitotag.com\/wp-content\/uploads\/2020\/07\/centro-2020_colored_b-2.png 315w, https:\/\/mitotag.com\/wp-content\/uploads\/2020\/07\/centro-2020_colored_b-2-300x73.png 300w\" sizes=\"(max-width: 315px) 100vw, 315px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-f33bfd8\" data-id=\"f33bfd8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-108b0f3 elementor-widget elementor-widget-image\" data-id=\"108b0f3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"229\" height=\"75\" src=\"https:\/\/mitotag.com\/wp-content\/uploads\/2020\/07\/portugal-2020_colored_b.png\" class=\"attachment-large size-large wp-image-1272\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-1cd2230\" data-id=\"1cd2230\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0c4fd03 elementor-widget elementor-widget-image\" data-id=\"0c4fd03\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"269\" height=\"78\" src=\"https:\/\/mitotag.com\/wp-content\/uploads\/2020\/07\/ue_colored_b.png\" class=\"attachment-large size-large wp-image-1270\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-84b3990 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"84b3990\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e01efe0\" data-id=\"e01efe0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ea3b0f1 elementor-widget elementor-widget-text-editor\" data-id=\"ea3b0f1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Designa\u00e7\u00e3o do projeto<\/strong> |MitoBOOST v2.0 &#8211; Prova de Conceito para o Uso de Polifen\u00f3is Dirigidos \u00e0 Mitoc\u00f4ndria para Tratar a Doen\u00e7a do F\u00edgado Gordo N\u00e3o-Alco\u00f3lico<br \/><br \/><strong>C\u00f3digo do projeto<\/strong> | CENTRO-01-0145-FEDER-181226<br \/><br \/><strong>Objetivo principal<\/strong> | Refor\u00e7ar a investiga\u00e7\u00e3o, o desenvolvimento tecnol\u00f3gico e<br \/>a inova\u00e7\u00e3o<\/p><p><strong>Regi\u00e3o de interven\u00e7\u00e3o<\/strong> | CENTRO<br \/><strong>Entidade benefici\u00e1ria<\/strong> | MITOTAG, LDA<\/p><p><strong>Data de aprova\u00e7\u00e3o<\/strong> | 08-06-2022<br \/><strong>Data de in\u00edcio<\/strong> | 01-07-2022<br \/><strong>Data de conclus\u00e3o<\/strong> | 30-06-2023<br \/><strong>Custo total eleg\u00edvel<\/strong> | 149.990,27 \u20ac<br \/><strong>Apoio financeiro da Uni\u00e3o Europeia (FEDER)<\/strong>| 124.168,98 \u20ac<\/p><p><strong>Objetivos, atividades e resultados esperados\/ atingidos<\/strong><\/p><p>O objetivo do presente projeto \u00e9 efetuar uma prova de conceito relativa ao uso de uma\u00a0 mol\u00e9cula nova, AntiOXBEN2, ainda em fase de pr\u00e9-cl\u00ednica, e que resultou de um projeto financiado pela Funda\u00e7\u00e3o Para a Ci\u00eancia e a Tecnologia (DTP- FTO\/2433\/2014), focado no desenvolvimento de uma nova terapia para a doen\u00e7a do f\u00edgado gordo n\u00e3o alco\u00f3lico. O presente projeto e prova de conceito, intitulado \u201cMitoBOOST v.2.0\u201d permitir\u00e1 obter evid\u00eancias da efic\u00e1cia e toxicidade do AntiOxBEN2, num modelo animal, assim como obten\u00e7\u00e3o de dados farmacocin\u00e9ticos e farmacodin\u00e2micos, que permitir\u00e3o a sua classifica\u00e7\u00e3o como candidato a f\u00e1rmaco, podendo ser depois ser valorizado para os subsequentes ensaios cl\u00ednicos de fase I.<\/p><p>\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f740465 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f740465\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7b50e97\" data-id=\"7b50e97\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7e8dd1e elementor-widget elementor-widget-progress\" data-id=\"7e8dd1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"progress.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<span class=\"elementor-title\" id=\"elementor-progress-bar-7e8dd1e\">\n\t\t\t\tExecu\u00e7\u00e3o de Projeto\t\t\t<\/span>\n\t\t\n\t\t<div aria-labelledby=\"elementor-progress-bar-7e8dd1e\" class=\"elementor-progress-wrapper\" role=\"progressbar\" aria-valuemin=\"0\" aria-valuemax=\"100\" aria-valuenow=\"100\">\n\t\t\t<div class=\"elementor-progress-bar\" data-max=\"100\">\n\t\t\t\t<span class=\"elementor-progress-text\"><\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-progress-percentage\">100%<\/span>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>|MitoBOOST v2.0 Designa\u00e7\u00e3o do projeto |MitoBOOST v2.0 &#8211; Prova de Conceito para o Uso de Polifen\u00f3is Dirigidos \u00e0 Mitoc\u00f4ndria para Tratar a Doen\u00e7a do F\u00edgado Gordo N\u00e3o-Alco\u00f3lico C\u00f3digo do projeto | CENTRO-01-0145-FEDER-181226 Objetivo principal | Refor\u00e7ar a investiga\u00e7\u00e3o, o desenvolvimento tecnol\u00f3gico ea inova\u00e7\u00e3o Regi\u00e3o de interven\u00e7\u00e3o | CENTROEntidade benefici\u00e1ria | MITOTAG, LDA Data de aprova\u00e7\u00e3o [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-1537","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mitotag.com\/index.php?rest_route=\/wp\/v2\/pages\/1537","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mitotag.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mitotag.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mitotag.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mitotag.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1537"}],"version-history":[{"count":10,"href":"https:\/\/mitotag.com\/index.php?rest_route=\/wp\/v2\/pages\/1537\/revisions"}],"predecessor-version":[{"id":1575,"href":"https:\/\/mitotag.com\/index.php?rest_route=\/wp\/v2\/pages\/1537\/revisions\/1575"}],"wp:attachment":[{"href":"https:\/\/mitotag.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1537"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}